I mean… If you have a ton of raw photos in one directory, you can enable the highest compression rate with zstd to it. Every other directory has lz4 with the fastest compression. Your pics take much less space, but the directory will be slower to read and write.
It is only in TLS where you have to disable compression, not in HTTP.
https://security.stackexchange.com/questions/19911/crime-how-to-beat-the-beast-successor/19914#19914
Could you explain how a CRIME attack can be done to a disk?